Preoperative localization and biopsy of exclusively MRI detectable breast lesions: Experiences with xx patients

METHODS: 118 exclusively MRI detectable breast lesions of 103 patients (age: 25 to 80 years, mean age: 50) were histologically proven by excisional biopsy after MRguided marking (n=89) or MR-guided microbiopsy (n=29). The interventional imaging was performed at 1 T (n=108) or 0.2 T (n=10). Lesion localization was carried out with an MR compatible metal coil (n=50) or a hook wire (n=39). Microbiopsies were performed with 14 G-high-speed biopsy systems. Prior to the interventional MRI every patient underwent diagnostic dynamic contrast-enhanced MRI of the breast (0.16 mmol Gd-DTPA/kg bw, double breast coil) by means of a T1w FLASH 3D-sequence. Different lesion characteristics (size, shape, margin, pattern of contrast enhancement) and BI-RADSTM-analogous categories depending on the degree of suspicion (3=probably benign, 4=suspicious, 5=highly suggestive of malignancy) were investigated by analysis of diagnostic MRI. Specificity and sensitivity of the contrast enhanced MRI were calculated and the relation between distinct lesion parameters and malignancy is discussed.